Endocrine Abstracts

Dyslipidemia is a frequent pathology, especially in diabetics, which may require the use of lipid-lowering drugs such as statins. Our goal is to determine the impact of these molecules on the metabolic profile of a diabetic population with dyslipidemia.Methods: This is a retrospective study including 150 patients followed at the Tunis nutrition institute for diabetes and dyslipidemia.Results: The average BMI was 31.4 ± 6.1 kg/...

Introduction: Diabetic neuropathy is a degenerative complication of diabetes mellitus which can be restrictive. The objective of our work is to determine the prevalence of this complication in a type 2 diabetic population as well as its different risk factorsMethods: This is a retrospective study including 100 Tunisian type 2 diabetic patients followed up in the ‘C’ department at the National Nutrition Institute in Tunis.<p class="abstext...

Introduction: Pseudoxanthoma elasticum (PXE), a multisystem heritable disorder, is characterized by ectopic mineralization of soft connective tissues. It is an autosomal recessive disorder in which mutations in the ABCC6 gene result in low levels of inorganic pyrophosphate (PPi).In its classic form, PXE is a late-onset, slowly progressing disease, and the major clinical problems relate to development of vascular complications, including hypertension, int...

Background and aimDiabetes is the leading cause of adult blindness due to retinopathy. Serum uric acid levels independently predict the development of micro vascular complications. In this study, we analyze the relationship between serum uric acid (SUA) levels with the development and the severity of diabetic retinopathy(DR) in patients with type 2 diabetes mellitus (T2DM).Patients and MethodsA total of 100 T...

Background and aimHyperuricemia is linked to a variety of diseases such as atherosclerotic cardiovascular disease (ASCVD). There are controversial data concerning the significance of high-normal values of serum uric acid (SUA) in patients with T2DM and cardiovascular disease. The aim of the study is to assess SUA levels in Type 2 diabetes mellitus (T2DM) patients with ASCVD.Patients and methodsThis retrospect...

BackgroundThere is a well-recognized association between diabetic retinopathy (DN) and diabetic nephropathy (DN), in which nephropathy without retinopathy is rare but retinopathy without nephropathy is common.AimTo highlight the discordance between retinopathy and nephropathy and describe a series of patients with diabetic nephropathy who had no evidence of diabetic retinopathy.Methods<...

IntroductionThe combination of at least three autoimmune diseases in the same patient is defined as multiple autoimmune syndrome. Recent studies demonstrated a higher prevalence of celiac disease in patients with immune thrombocytopenia when compared to the general population. Here we report the occurrence of celiac disease, Hashimoto’s disease and immune thrombocytopenia in type 2 diabetes patient.Case report<p class="abs...

Background and aimAbundant evidence suggests an association between thyroid disease and type 2 diabetes mellitus (T2DM). To determine the interaction between these co-existing pathologies, we analyzed insulin-treated type 2 diabetes patients with diagnosed thyroid disease.Patients and methodsThis retrospective study was performed in 54 type 2 diabetes patients who had been admitted for insulin-treatment and d...

BackgroundCeliac disease (CD) occurs in patients with type1 diabetes (T1DM) ranging the prevalence of 4.4–11.1% versus 0.5% of the general population. The mechanism of association of these two diseases involves a shared genetic background.AimTo investigate whether in type1 diabetes (T1DM) patients the concomitance of treated celiac disease (CD) impacts glycemic control and the prevalence of microvascular...

Background and aim: Gestational Diabetes Mellitus (GDM) is the commonest medical pregnancy complication. Nutritional interventions come to the fore as one of the few levers for managing GDM, as many medications are either harmful to the growing fetus, or their toxicity is uncertain. The aim of this study was to assess the potential clinical features and nutritional risk factors of insulin treatment during GDM.Methods: This was a prospective study includ...